Deficiencies of B6, folate, and B12 increase which levels in the blood that are a risk factor for atherosclerosis?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $25.99Unlock all

Study for the CVP and GI Pathology Exam 1. Engage with flashcards and multiple-choice questions, each with hints and explanations. Prepare thoroughly for your test!

Multiple Choice

Deficiencies of B6, folate, and B12 increase which levels in the blood that are a risk factor for atherosclerosis?

Explanation:
Deficiencies of B6, folate, and B12 cause elevated homocysteine in the blood, which increases the risk for atherosclerosis. Folate and B12 are essential cofactors for remethylating homocysteine back to methionine, while B6 is a key cofactor for the transsulfuration pathway that converts homocysteine to cystathionine. When these pathways are impaired, homocysteine accumulates, promoting endothelial injury, oxidative stress, and vascular changes that drive atherogenesis. Uric acid, glucose, and LDL cholesterol levels are not directly driven by these B vitamin deficiencies in the same way, so they don’t specifically reflect the effect of insufficient B6, folate, and B12.

Deficiencies of B6, folate, and B12 cause elevated homocysteine in the blood, which increases the risk for atherosclerosis. Folate and B12 are essential cofactors for remethylating homocysteine back to methionine, while B6 is a key cofactor for the transsulfuration pathway that converts homocysteine to cystathionine. When these pathways are impaired, homocysteine accumulates, promoting endothelial injury, oxidative stress, and vascular changes that drive atherogenesis. Uric acid, glucose, and LDL cholesterol levels are not directly driven by these B vitamin deficiencies in the same way, so they don’t specifically reflect the effect of insufficient B6, folate, and B12.

More Multiple Choice Questions
Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy